Placental Circulation

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Placental compliance during fetal extracorporeal circulation.

The fetus requires large amounts of volume when weaning from cardiac bypass. This suggests that placental vasculature can act as a large capacitor in the fetal circulation. To assess placental compliance of fetal lambs, seven isolated in situ lamb placentas were placed on extracorporeal circulation. Umbilical artery blood flow was varied from 0 to 350 ml. min(-1). kg fetal wt(-1). Because the e...

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Insignificant response of the fetal placental circulation to arterial hypotension in sheep.

Infusion of the angiotensin-converting enzyme inhibitor enalaprilat into fetal sheep caused a profound arterial hypotension within days. Five fetal lambs were infused with enalaprilat for 8 days starting at day 128 of gestation. Total accumulated dose was 0.30 ± 0.11 mg/kg. Arterial pressure decreased from 43.6 to 25.6 mmHg; venous pressure did not change. Biventricular output was not statistic...

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Does Antenatal Maternal Psychological Distress Affect Placental Circulation in the Third Trimester?

INTRODUCTION Some types of antenatal maternal psychological distress may be associated with reduced fetal growth and birthweight. A stress-mediated reduction in placental blood flow has been suggested as a mechanism. Previous studies have examined this using ultrasound-derived arterial resistance measures in the uterine (UtA) and umbilical (UA) arteries, with mixed conclusions. However, a reduc...

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Maternal Psychological Distress and Placental Circulation in Pregnancies after a Previous Offspring with Congenital Malformation

INTRODUCTION Antenatal maternal psychological distress may be associated with reduced placental circulation, which could lead to lower birthweight. Studies investigating this in humans show mixed results, which may be partially due to type, strength and timing of distress. In addition, the arterial vascular resistance measures often used as outcome measures do not detect smaller changes in plac...

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Development of a placental blood circulation in rat embryos in vitro.

Rat embryos explanted with their membranes at head-fold stage (9 1/2 days gestation) formed an allantoic placenta which enlarged in culture and developed a foetal blood circulation. Embryos explanted at early somite stages (10 1/2 days) also formed a growing allantoic placenta but only after removal of most of the ectoplacental trophoblast. Assays of total protein in the embryo and placenta sug...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1944

ISSN: 0035-9157

DOI: 10.1177/003591574403700815